The Binding of Isaac Four Souls TCG

Enter the chaotic and darkly humorous world of The Binding of Isaac: Four Souls, the tabletop card game where sacrifice, betrayal, and treasure combine in a race for power. Designed by Edmund McMillen, this game drops 2–4 players into Isaac’s unsettling universe: you’ll collect loot, fight monsters, and gather souls, all while dealing with your rivals’ schemes. Each character brings unique abilities, items, and strategies, making every session unpredictable—will you betray your friends to snatch victory, or band together only to turn on each other at the end? The first player to hold four souls wins, but getting there means mastering risk, resource management, and timing. With over 300 cards in the base game plus expansions packed with new monsters, items, and mechanics, every game offers rich replayability and blistering tension. Dare to dive in?